Publikationsdatenbank

Agricultural fertilization with poultry manure results in persistent environmental contamination with the pathogen Clostridioides difficile (2021)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Frentrup, Martinique

Thiel, Nadine

Junker, Vera

Behrens, Wiebke

Münch, Steffen

Siller, Paul (WE 10)

Kabelitz, Tina

Faust, Matthias

Indra, Alexander

Baumgartner, Stefanie

Schepanski, Kerstin

Amon, Thomas (WE 10)

Roesler, Uwe (WE 10)

Funk, Roger

Nübel, Ulrich

Forschungsprojekt

Ausbreitung von Antibiotikaresistenzen auf landwirtschaftlich genutzten Flächen (Akronym: SoARIAL)

Quelle

Environmental microbiology

Bandzählung: 23

Heftzählung: 12

Seiten: 7591 – 7602

ISSN: 1462-2912

Sprache

Englisch

Verweise

URL (Volltext): https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.15601

DOI: 10.1111/1462-2920.15601

Pubmed: 33998128

Kontakt

Institut für Tier- und Umwelthygiene

Robert-von-Ostertag-Str. 7-13
14169 Berlin
+49 30 838 51845
tierhygiene@vetmed.fu-berlin.de

Abstract / Zusammenfassung

During a field experiment applying broiler manure for fertilization of agricultural land, we detected viable Clostridioides (also known as Clostridium) difficile in broiler faeces, manure, dust and fertilized soil. A large diversity of toxigenic C. difficile isolates was recovered, including PCR ribotypes common from human disease. Genomic relatedness of C. difficile isolates from dust and from soil, recovered more than 2 years after fertilization, traced their origins to the specific chicken farm that had delivered the manure. We present evidence of long-term contamination of agricultural soil with manure-derived C. difficile and demonstrate the potential for airborne dispersal of C. difficile through dust emissions during manure application. Clostridioides genome sequences virtually identical to those from manure had been recovered from chicken meat and from human infections in previous studies, suggesting broiler-associated C. difficile are capable of zoonotic transmission.