Publikationsdatenbank

Chronic heart failure due to severe endocardiosis in a Gambian giant pouched rat (Cricetomys gambianus) (2010)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Müller, Kerstin

Horn, Britta

Fritsch, Guido

Range, Friederike

Klopfleisch, Robert

Quelle

Journal of zoo and wildlife medicine : official publ. of the American Association of Zoo Veterinarians

Bandzählung: 41

Heftzählung: 1

Seiten: 137 – 139

ISSN: 1042-7260

Sprache

Englisch

Verweise

Pubmed: 20722267

Kontakt

Klein- und Heimtierklinik

Oertzenweg 19 b
14163 Berlin
+49 30 838 62422
kleintierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

A 1.5-yr-old captive male Gambian giant pouched rat (Cricetomys gambianus) died after suffering from anorexia, weakness, and dyspnea for 3 wk. Thoracic radiographs of thorax and abdomen and computed tomography showed a severe biventricular enlargement of the heart and a moderate hepatomegaly. Necropsy revealed a severe, bilateral hypertrophic cardiomyopathy and dilation of the right ventricle due to multifocal bilateral, valvular endocardiosis of all atrioventricular valves and acute hepatic congestion. Histologically, the atrioventricular valves were multifocally thickened by a marked endocardiosis with stromal accumulation of Periodic acid-Schiff (PAS)-positive, mucinous material. Although common in dogs, endocardiosis has not been described in Nesomyidaes. As in other affected species, the pathogenesis of endocardiosis in this species remains unclear.