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    Advances in modeling of the bovine estrous cycle:
    synchronization with PGF2α (2012)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Stötzel, C.
    Plöntzke, J.
    Heuwieser, W.
    Röblitz, S.
    Quelle
    Theriogenology; 78(7) — S. 1415–1428
    ISSN: 0093-691x
    Sprache
    Englisch
    Verweise
    DOI: 10.1016/j.theriogenology.2012.04.017
    Pubmed: 22980082
    Kontakt
    Tierklinik für Fortpflanzung

    Königsweg 65
    Haus 27
    14163 Berlin
    +49 30 838 62618
    fortpflanzungsklinik@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Our model of the bovine estrous cycle is a set of ordinary differential equations which generates hormone profiles of successive estrous cycles with several follicular waves per cycle. It describes the growth and decay of the follicles and the corpus luteum, as well as the change of the key reproductive hormones, enzymes and processes over time. In this work we describe recent developments of this model towards the administration of prostaglandin F2α. We validate our model by showing that the simulations agree with observations from synchronization studies and with measured progesterone data after single dose administrations of synthetic prostaglandin F2α.