Publikationsdatenbank

Leukoencephalomalacia and laminar neuronal necrosis following smoke inhalation in a dog (2011)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Weiss, A. Th. A. (WE 12)

Graf, C. (WE 20)

Gruber, A. D. (WE 12)

Kohn, B. (WE 20)

Quelle

Veterinary pathology : an internat. journal of natural and experimental disease in animals

Bandzählung: 48

Heftzählung: 5

Seiten: 1016 – 1019

ISSN: 0300-9858

Sprache

Englisch

Verweise

URL (Volltext): https://journals.sagepub.com/doi/10.1177/0300985810384412

DOI: 10.1177/0300985810384412

Pubmed: 20940447

Kontakt

Klein- und Heimtierklinik

Oertzenweg 19 b
14163 Berlin
+49 30 838 62422
kleintierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Acute respiratory and neurologic disease after smoke inhalation are well documented, but human patients may also develop delayed-onset neurologic symptoms associated with leukoencephalomalacia after exposure to smoke or carbon monoxide. In this case, a dog developed progressive neurologic signs 6 days after rescue from an apartment fire. At necropsy 9 days after smoke inhalation, leukoencephalomalacia of the central cerebral white matter was accompanied by laminar necrosis of cerebrocortical neurons. This is the first report of delayed posthypoxic leukoencephalopathy in a nonhuman animal.