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    Ruminal transport of SCFA (2010)

    Art
    Vortrag
    Autoren
    Stumpff, F
    Martens, H
    Gäbel, G
    Kongress
    19. Symposium der Fachgruppe Physiologie und Biochemie der Deutschen Veterinärmedizinischen Gesellschaft
    Hannover, 14. – 16.02.2010
    Quelle
    19. Symposium der Fachgruppe Physiologie und Biochemie der Deutschen Veterinärmedizinischen Gesellschaft; Proc. Fachgruppe Physiologie und Biochemie der DVG — Deutsche Veterinärmedizinische Gesellschaft (Hrsg.)
    Gießen: Verlag DVG Service, 2010 — S. 36–41
    ISBN: 978-3-941703-55-1
    Kontakt
    Institut für Veterinär-Physiologie

    Oertzenweg 19 b
    14163 Berlin
    Tel.+49 30 838 62600 Fax.+49 30 838-62610
    email:physiologie@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Fermentational processes in the rumen release large amounts of short chain fatty acids (SCFA) that are absorbed locally and enter the portal blood. Absorption is transcellular and increases with decreasing mucosal pH and increasing chain length. Current models suggest both diffusive uptake as HSCFA and as the anion in exchange for HCO3-, with modulation by a pH-microclimate within the stratum corneum. Protons taken up with SCFA are rapidly recycled to the rumen via NHE in exchange for Na+, which leaves basolaterally via the Na+-K+-ATPase. The potential generated across the basolateral membrane drives efflux through a large conductance anion channel with high permeability for chloride, acetate and propionate. The permeability for butyrate is poor and thus, this SCFA is largely metabolized into substrates that leave via basolateral monocarboxylate transport (MCT).