Publikationsdatenbank

Ruminal transport of SCFA (2010)

Art

Vortrag

Autoren

Stumpff, F

Martens, H

Gäbel, G

Kongress

19. Symposium der Fachgruppe Physiologie und Biochemie der Deutschen Veterinärmedizinischen Gesellschaft

Hannover, 14. – 16.02.2010

Quelle

19. Symposium der Fachgruppe Physiologie und Biochemie der Deutschen Veterinärmedizinischen Gesellschaft; Proc. Fachgruppe Physiologie und Biochemie der DVG — Deutsche Veterinärmedizinische Gesellschaft (Hrsg.)

Gießen: Verlag DVG Service, 2010 — S. 36–41

ISBN: 978-3-941703-55-1

Kontakt

Institut für Veterinär-Physiologie

Oertzenweg 19 b
14163 Berlin
+49 30 838 62600
physiologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Fermentational processes in the rumen release large amounts of short chain fatty acids (SCFA) that are absorbed locally and enter the portal blood. Absorption is transcellular and increases with decreasing mucosal pH and increasing chain length. Current models suggest both diffusive uptake as HSCFA and as the anion in exchange for HCO3-, with modulation by a pH-microclimate within the stratum corneum. Protons taken up with SCFA are rapidly recycled to the rumen via NHE in exchange for Na+, which leaves basolaterally via the Na+-K+-ATPase. The potential generated across the basolateral membrane drives efflux through a large conductance anion channel with high permeability for chloride, acetate and propionate. The permeability for butyrate is poor and thus, this SCFA is largely metabolized into substrates that leave via basolateral monocarboxylate transport (MCT).