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    Non-metastatic squamous cell carcinoma in two Hermann’s tortoises (Testudo hermanni) (2012)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Deetzen, M v (WE 12)
    Müller, Kerstin (WE 20)
    Brunnberg, Leo (WE 20)
    Klopfleisch, R (WE 12)
    Quelle
    Veterinary Science Development; 2(1) — S. 17–19
    ISSN: 2038-9701
    Sprache
    Englisch
    Verweise
    URL (Volltext): http://edocs.fu-berlin.de/docs/receive/FUDOCS_document_000000019790
    DOI: 10.4081/vsd.2012.e5
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    Abstract / Zusammenfassung

    Squamous cell carcinomas (SCC) are malignant tumors of the epidermal cells with varying degrees of keratinocyte differentiation. They are common tumors in mammalian and avian species but there are, however, only two description of SCC in tortoises. In this case report we describe two cases of non-metastatic squamous cell carcinomas of the carapax and the plastron in Hermann’s tortoises with evidence of humoral hypercalcemia of malignancy (HHM) in one case. HHM is thought to be associated with SCC in mammals due to de novo secretion of parathyroid hormone-related protein (PTHrP) by the tumor cells or tumor induced osteolysis but has not been described in reptiles so far.