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    Does artificial intelligence influence pathologists' decisions?
    a study on the anchoring bias in computer-assisted mitotic figure assessment by veterinary pathologists (2026)

    Art
    Poster
    Autoren
    Conrad, T. (WE 12)
    Banerjee, S.
    Rosbach, E.
    Doherr, M. G. (WE 16)
    Bartenschlager, F. (WE 12)
    Bolfa, P.
    de Brot, S.
    Bünger, M. (WE 12)
    Donovan, T. A.
    Eddicks, L.
    Fiedler, S.
    Gager, A. M.
    Haake, A. F. H. (WE 12)
    Hanselmann, L. K. (WE 12)
    Kolb, N.
    Landmann, K. (WE 12)
    Pischon, H.
    Radbruch, M.
    Weiss, V.
    Ammeling, J.
    Kaltenecker, C.
    Stroblberger, C.
    Aubreville, M.
    Betram, C. A.
    Klopfleisch, R. (WE 12)
    Kongress
    ESVP/ECVP/ESVCP/ECVCP Congress 2026
    Nantes, France, 16. – 19.09.2026
    Quelle
    Annual ESVP/ECVP/ESVCP/ECVCP Congress 2026 : Proceedingsbook
    — S. 288–289
    Sprache
    Englisch
    Verweise
    URL (Volltext): https://www.esvp-ecvp-estp-congress.eu/resources/media/ESVP_2026/20260901_ESVP-ECVP-ESVCP-ECVCP_Proceedingsbook_2026.pdf
    Kontakt
    Institut für Veterinär-Epidemiologie und Biometrie

    Königsweg 67
    14163 Berlin
    +49 30 838 56034
    epi@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Background:
    Reliable mitotic figure identification is essential for mitotic count assessment in histological tumour sections but shows substantial observer variability. Artificial intelligence (AI) has been shown to improve reproducibility, but AI-generated suggestions may bias pathologists' interpretation. This study evaluated whether veterinary pathologists shift their judgements toward displayed AI-attributed confidence scores when assessing mitotic figures in canine cutaneous mast cell tumours.
    Materials & Methods:
    Fourteen pathologists scored 500 H&E image patches, each containing a mitotic figure candidate, over three rounds on a 0–100 scale. Scores >50 indicated a mitotic figure and scores <50 indicated no mitotic figure. Two unaided rounds assessed intra-rater variability. In the final round, AI-attributed confidence scores were displayed with the images. These scores were not calculated by a real AI model but were based on each participant's previous ratings and systematically shifted by +/-15, +/-25, or +/-35 points.
    Results:
    The two unaided rounds showed moderate agreement (intraclass correlation coefficient [ICC] = 0.648, 95% confidence interval [CI] 0.634–0.661), and median absolute intraobserver variability was 10 points. In the AI-supported round, participants shifted their ratings significantly toward the displayed AI-attributed values, with larger discrepancies causing larger shifts in the same direction (beta = 0.118, 95% CI 0.101–0.136, p < 0.001). However, this did not increase binary classification switches beyond unaided variability (22.8% vs. 20.3%).
    Conclusion:
    AI-attributed confidence scores caused a statistically significant but small anchoring effect on veterinary pathologists' assessments. However, the results indicate that the AIassisted approach did not negatively impact the pathologists' ability to interpret mitotic figure morphologies.