Publikationsdatenbank

Staphylococcus aureus in Rwandan dogs predominantly representing human-associated lineages (2025)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Marek, Lydia

Irimaso, Emmanuel

Turikumwenayo, Jean Bosco

Mukamulisa, Beatrice

Ndishimye, Prudence

Muragijemariya, Flora

Cabal-Rosel, Adriana

Desvars-Larrive, Amelie

Fischer, Otto W.

Szostak, Michael P.

Müller, Elke

Braun, Sascha D.

Ehling-Schulz, Monika

Spergser, Joachim

Grunert, Tom

Ruppitsch, Werner

Feßler, Andrea T. (WE 7)

Schwarz, Stefan (WE 7)

Monecke, Stefan

Ehricht, Ralf

Künzel, Frank

Loncaric, Igor

Quelle

Letters in Applied Microbiology

Bandzählung: 78

Heftzählung: 5

Seiten: Artikel ovaf065 (8 Seiten)

ISSN: 0266-8254

Sprache

Englisch

Verweise

URL (Volltext): https://academic.oup.com/lambio/article/78/5/ovaf065/8120510

DOI: 10.1093/lambio/ovaf065

Pubmed: 40287395

Kontakt

Institut für Mikrobiologie und Tierseuchen

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51843 / 66949
mikrobiologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

The present study aimed at examining the nasal and ear carriage of Staphylococcus aureus of Rwandan dogs and cats. Sixty-five S. aureus isolates were detected, all originating from the nostrils of dogs. Resistance to penicillin, penicillin/erythromycin/clindamycin, penicillin/tetracycline, and tetracycline solely was observed. The isolates were assigned to 23 different spa types, among them three novel (t21589, t21661, and t21662) variants, associated with eleven clonal complexes (CCs) (CC1, CC5, CC12, CC15, CC22, CC30, CC45, CC97, CC152, CC707, and CC834). Four isolates could not be assigned to any known CC. MLST revealed that one of them belonged to the new sequence type (ST) 9069. Panton-Valentine leukocidin (PVL) genes (lukF-PV/lukS-PV), the bovine leukocidin genes (lukM/lukF-P83), the toxic shock syndrome toxin gene tst-1, and various virulence-associated genes were detected. These findings demonstrate the dogs are colonized with human lineages of S. aureus. Coupled with the limited availability of S. aureus data from human medicine in Rwanda underscores the importance of hygiene measures and supports the need for a rigorous One-Health Surveillance program of the companion animals-human interface.