Publikationsdatenbank

Dietary fibre and weaning age influence morphology, mucin distribution, and immunological traits in the porcine colon (2025)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Yu, Xiaoxiao

Martinez Vallespin, Beatriz (WE 4)

Grześkowiak, Łukasz (WE 4)

Rothkötter, Hermann-Josef

Vahjen, Wilfried (WE 4)

Saliu, Eva-Maria (WE 4)

Zentek, Jürgen (WE 4)

Schulze Holthausen, Johannes (WE 4)

Quelle

Journal of functional foods

Bandzählung: 131

Seiten: Artikel 106947 (11 Seiten)

ISSN: 1756-4646

Sprache

Englisch

Verweise

URL (Volltext): https://www.sciencedirect.com/science/article/pii/S1756464625002890?via%3Dihub

DOI: 10.1016/j.jff.2025.106947

Kontakt

Institut für Tierernährung

Königin-Luise-Str. 49
14195 Berlin
+49 30 838 52256
tierernaehrung@vetmed.fu-berlin.de

Abstract / Zusammenfassung

This study investigated the effects of dietary fibre type, particle size, and weaning age on colonic morphology, mucin distribution, and immune function in piglets. Ninety-four piglets were assigned to groups based on weaning age (28 ± 2 days, conventional weaning, CW; 42 ± 2 days, late weaning, LW) and fed diets with hay or sugar beet pulp (SBP, fine or coarse particles). After two weeks, tissue samples were collected. SBP enhanced the expression of IL-10 (P = 0.001) and GPR43 mRNA (P = 0.029), while it enhanced mucin presence in LW piglets (P < 0.01). In LW piglets, coarse particles increased crypt area (P = 0.012), and fine particles increased immune cell infiltration. Weaning age also affected crypt morphology and goblet cell numbers, with LW piglets showing deeper crypts (P < 0.001). Results suggest that fibre type, particle size, and weaning age significantly influence gut health and immunity.