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This special edition of the E-methodology journal and conference, marking its 10th anniversary, explores the dynamic intersection of technology, science, and society. Dur- ing a decade we have seen a revolution in the meaning of “e” from being just a digi- tal version of human activity to a totally new world of LLMs (Large Language Models) and other deep learning possibilities. The articles in this volume delve mainly into the transformative potential of artificial intelligence (AI) across diverse fields such as forensic science, education, healthcare, One Health, and public discourse, while examining the broader implications of technology on human life.