Publikationsdatenbank

Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals? (2023)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Sehrawat, Sharvan

Osterrieder, Klaus (WE 5)

Schmid, D. Scott

Rouse, Barry T.

Quelle

Microbes and infection : a journal on infectious agents and host defenses

Bandzählung: 25

Heftzählung: 1-2

Seiten: 105078

ISSN: 1769-714x

Sprache

Englisch

Verweise

URL (Volltext): https://pubmed.ncbi.nlm.nih.gov/36435367/

DOI: 10.1016/j.micinf.2022.105078

Pubmed: 36435367

Kontakt

Institut für Virologie

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51833
virologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

The unprecedented success of mRNA vaccines in managing the COVID-19 pandemic raises the prospect of applying the mRNA platform to other viral diseases of humans and domesticated animals, which may lead to more efficacious vaccines for some agents. We briefly discuss reasons why mRNA vaccines achieved such success against COVID-19 and indicate what other virus infections and disease conditions might also be ripe for control using mRNA vaccines. We also evaluate situations where mRNA could prove valuable to rebalance the status of immune responsiveness and achieve success as a therapeutic vaccine approach against infections that induce immunoinflammatory lesions.