Publikationsdatenbank

Anti-HEV seroprevalence and rate of Viremia in a German cohort of dogs, cats, and horses (2023)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Pischke, S.

Knoop, E. V.

Mader, M.

Kling, L.

Wolski, A.

Wagner, A.

Müller, Kerstin (WE 20)

Horvatits, T.

Stiller, J.

Wisnewski, K.

Kohn, Barbara (WE 20)

Schulze Zur Wiesch, J.

Groschup, M. H.

Eiden, M.

Quelle

Scientific reports

Bandzählung: 13

Heftzählung: 1

Seiten: 19240

ISSN: 2045-2322

Sprache

Englisch

Verweise

URL (Volltext): https://pubmed.ncbi.nlm.nih.gov/37935733/

DOI: 10.1038/s41598-023-46009-y

Pubmed: 37935733

Kontakt

Klein- und Heimtierklinik

Oertzenweg 19 b
14163 Berlin
+49 30 838 62422
kleintierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Hepatitis E virus (HEV) genotype 3 infections in Germany are mainly transmitted zoonotically through the consumption of swine meat. Furthermore, there is evidence that pets might come into contact with HEV, but the relevance of companion animals as possible sources of HEV transmission in Germany still needs to be defined. A monitoring study was therefore carried out on dogs, cats, and horses from Germany. In total 365 serum samples from pets (124 dogs, 119 cats, and 122 horses) were tested for HEV by PCR and for anti-HEV antibodies by a commercial ELISA. The HEV seroprevalence determined by the sero-assay varied significantly between dogs (10%), cats (6%), and horses (2%). Liver injury-related enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) showed no differences between HEV-positive or negative animals. None of the pet serum samples tested positive for PCR. This serological study suggests that dogs and cats are significantly exposed to HEV in Germany, while horses are of minor relevance.