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    Mapping subchondral bone density distribution in the canine C6-C7 vertebral endplates:
    a CT-OAM study (2023)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Kramer, Vincenz (WE 20)
    Böttcher, Peter (WE 20)
    Quelle
    Animals
    Bandzählung: 13
    Heftzählung: 22
    Seiten: Artikel 3432
    ISSN: 2076-2615
    Sprache
    Englisch
    Verweise
    URL (Volltext): https://pubmed.ncbi.nlm.nih.gov/38003050/
    DOI: 10.3390/ani13223432
    Pubmed: 38003050
    Kontakt
    Klein- und Heimtierklinik

    Oertzenweg 19 b
    14163 Berlin
    +49 30 838 62422
    kleintierklinik@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Intervertebral cage subsidence is a common complication in treating disc-associated cervical spondylomyelopathy in dogs. The mechanical stability of the vertebral endplate in contact with the cage is crucial to preventing subsidence. This study aims to assess subchondral bone mineral density (sBMD) in the canine vertebral endplate (specifically, the C6-C7 vertebral motion unit) as a measure of its mechanical stability. The sBMD distribution was mapped for the C6 caudal and C7 cranial vertebral endplates in 15 middle- to large-breed dogs using computed tomography osteoabsorptiometry. The sBMD distribution in the canine C6 and C7 vertebral endplates exhibited a heterogeneous pattern, with lower density observed in the central and dorsal contact areas of the nucleus pulposus, where common subsidence occurs. Our results suggest a potential need to redesign intervertebral cages to ensure that contact areas align with regions of higher bone density. A broad-based design extending toward the lateral and dorsal aspects of the annulus fibrosus contact area may enhance stability.