Publikationsdatenbank

Blood-based markers for skeletal and cardiac muscle function in eventing horses before and after cross-country rides and how they are influenced by plasma volume shift (2023)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Giers, Johanna (WE 17)

Bartel, Alexander (WE 16)

Kirsch, Katharina

Müller, Simon Franz

Horstmann, Stephanie

Gehlen, Heidrun (WE 17)

Quelle

Animals

Bandzählung: 13

Heftzählung: 19

Seiten: Artikel 3110

ISSN: 2076-2615

Sprache

Englisch

Verweise

URL (Volltext): https://www.mdpi.com/2076-2615/13/19/3110

DOI: 10.3390/ani13193110

Pubmed: 37835716

Kontakt

Institut für Veterinär-Epidemiologie und Biometrie

Königsweg 67
14163 Berlin
+49 30 838 56034
epi@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Horses competing in cross-country tests are subjected to high physical demands. Within the scope of this prospective longitudinal study, blood values of 20 elite eventing horses were examined before and after two- to four-star cross-country rides. The aim was to find out whether blood-based markers for skeletal muscle and cardiac muscle function change after cross-country exercise. Parameters that provide information about fluid balance, muscle enzymes, metabolites and cardiac muscle-specific markers were investigated. We developed an approach to eliminate the concentration changes caused by reduced plasma volume. Parameters were measured pre, 10 and 30 min post exercise and the next morning and were evaluated using a mixed model. Thirty minutes after exercise, most parameter concentrations changed in an exercise-dependent manner. The next morning, most exercise-related markers recovered rapidly, while creatine kinase (CK) (26% increase; p = 0.008) and lactate dehydrogenase (LDH) (15% increase; p < 0.001) showed a declining but sustained increase. Cardiac troponin I (cTnI) increased above the reference range in 40 of the 55 rides (73%) and in 18 of 20 horses in the morning after exercise.