Publikationsdatenbank

Comparative study of digital squamous cell carcinoma in giant, standard, and miniature schnauzers (2023)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Aupperle-Lellbach, Heike

Heidrich, Daniela

Conrad, David

Beitzinger, Christoph

Masala, Nives

Klopfleisch, Robert (WE 12)

Müller, Tobias

Quelle

Animals

Bandzählung: 13

Heftzählung: 12

Seiten: Artikel 1990

ISSN: 2076-2615

Sprache

Englisch

Verweise

URL (Volltext): https://www.mdpi.com/2076-2615/13/12/1990

DOI: 10.3390/ani13121990

Pubmed: 37370500

Kontakt

Institut für Tierpathologie

Robert-von-Ostertag-Str. 15
14163 Berlin
+49 30 838 62450
pathologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

In schnauzers, a breed predisposition to squamous cell carcinoma of the digit (dSCC) is well known. The aim of this study was to compare the clinical and macroscopic findings of dSCCs in giant (GSs), standard (SSs), and miniature schnauzers (MSs). Methods: Pathology reports of 478 dSCCs from 417 schnauzers (227 GSs, 174 SSs, and 16 MSs) were retrospectively evaluated. Results: The MSs were older than the SSs and GSs (p ≤ 0.01). The male GSs were predisposed to dSCC (p < 0.05). In the GSs, the nodular dSCCs were larger than in the MSs (p ≤ 0.05) and SSs (p ≤ 0.001). The digital SCCs were mostly diagnosed at the forelimbs, especially at digits 1, 2, and 5. At the hindlimbs, the affected toes differed between the GSs and SSs. Multiple dSCCs were more common in SSs than in GSs (p = 0.003). If dSCC was the cause of death, the survival time was shorter than in dogs dying from other diseases (p = 0.004). Metastases occurred in 20% of the cases and led to a significantly shorter survival time in both the GSs and SSs (p < 0.001). Conclusions: The results showed various differences in the dSCC depending on the size variant of the schnauzer.