Publikationsdatenbank

Cold case: the disappearance of Egypt bee virus, a fourth distinct master strain of deformed wing virus linked to honeybee mortality in 1970's Egypt (2022)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

de Miranda, Joachim R.

Brettell, Laura E.

Chejanovsky, Nor

Childers, Anna K.

Dalmon, Anne

Deboutte, Ward

de Graaf, Dirk C.

Doublet, Vincent

Gebremedhn, Haftom

Genersch, Elke (WE 7)

Gisder, Sebastian

Granberg, Fredrik

Haddad, Nizar J.

Kaden, Rene

Manley, Robyn

Matthijnssens, Jelle

Meeus, Ivan

Migdadi, Hussein

Milbrath, Meghan O.

Mondet, Fanny

Remnant, Emily J.

Roberts, John M. K.

Ryabov, Eugene V.

Sela, Noa

Smagghe, Guy

Somanathan, Hema

Wilfert, Lena

Wright, Owen N.

Martin, Stephen J.

Ball, Brenda V.

Quelle

Virology journal

Bandzählung: 19

Heftzählung: 1

Seiten: Article number: 12

ISSN: 1743-422x

Sprache

Englisch

Verweise

URL (Volltext): https://virologyj.biomedcentral.com/articles/10.1186/s12985-022-01740-2

DOI: 10.1186/s12985-022-01740-2

Pubmed: 35033134

Kontakt

Institut für Mikrobiologie und Tierseuchen

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51843 / 66949
mikrobiologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

In 1977, a sample of diseased adult honeybees (Apis mellifera) from Egypt was found to contain large amounts of a previously unknown virus, Egypt bee virus, which was subsequently shown to be serologically related to deformed wing virus (DWV). By sequencing the original isolate, we demonstrate that Egypt bee virus is in fact a fourth unique, major variant of DWV (DWV-D): more closely related to DWV-C than to either DWV-A or DWV-B. DWV-A and DWV-B are the most common DWV variants worldwide due to their close relationship and transmission by Varroa destructor. However, we could not find any trace of DWV-D in several hundred RNA sequencing libraries from a worldwide selection of honeybee, varroa and bumblebee samples. This means that DWV-D has either become extinct, been replaced by other DWV variants better adapted to varroa-mediated transmission, or persists only in a narrow geographic or host range, isolated from common bee and beekeeping trade routes.