Publikationsdatenbank

Etiologic diagnosis in horses with equine recurrent uveitis (ERU) in Berlin Brandenburg, Germany (2023)

Art

Poster

Autoren

Kirmse, Lena (WE 20)

Thieme, Katharina (WE 20)

Eule, Johanna C. (WE 20)

Kongress

Annual Scientific Meeting of the European College of Veterinary Ophthalmologists

Salzburg, Austria, 02. – 05.06.2022

Quelle

Veterinary Ophthalmology : an international journal of clinical and investigative ophthalmology

Bandzählung: 26

Heftzählung: 4

Seiten: e36

ISSN: 1463-5216

Verweise

URL (Volltext): https://onlinelibrary.wiley.com/doi/10.1111/vop.13056

DOI: 10.1111/vop.13056

Kontakt

Klein- und Heimtierklinik

Oertzenweg 19 b
14163 Berlin
+49 30 838 62422
kleintierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Purpose:
To estimate etiologies in horses suffering from ERU and to compare different diagnostic procedures in the detection of intraocular infections.

Methods:
80 horses located in eastern Germany with a history of uveitis underwent a complete ophthalmic examination by a DECVO. Besides various breeds, 34 German Warmblood horses and 10 Icelandic horses were seen. Serum (S) and aqueous humor (AH) were collected. PCR testing for Leptospira spp., EHV-1 and EHV-4 were done on the AH (n = 80). Titer against Leptospira spp. were detected using MAT (n = 80) and/or ELISA (n = 44) on S and AH. Horses were assigned positive on a positive PCR result and/or serology when intraocular titers (either MAT or ELISA) were at least two folds higher than serum titers. Logistic regression analysis was used to compare status of intraocular leptospira infection between breeds.

Results:
52/80 (65.0%) horses were diagnosed to be infected with intraocular Leptospira spp. (30.8%, 16/52 by PCR; 90.4%, 47/52 by titer (MAT 38/52, ELISA 13/43)). L. interrogans serovar Grippotyphosa was determined as the most common intraocular serovar in 32/47 horses (68.1%). No EHV was detected. Odds ratio of being infected with intraocular leptospirosis was 2.545 for Icelandic horses (8/10 (80%) vs. 22/36 (61.1%), p = 0.278) and 1.167 for German Warmblood horses (22/34 (64.7%) vs. 22/36 (61.1%), p = 0.756) compared to horses of other breeds.

Conclusion:
Intraocular leptospirosis or intraocular infections with Leptospira spp. was diagnosed in two thirds of the patients. Icelandic horses were 2.6 times more likely to be positive for intraocular leptospirosis than horses of other breeds.