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Open science has become a slogan in the scientific community that that too often fails in its practical implementation. Here we provide an overview of practices that can be applied throughout the research process to help scientists improve the transparency and quality of their work. As open science practices continue to evolve, we also provide an online toolbox of resources that we will continually update. This toolbox can be accessed through Zenodo (DOI:10.5281/zenodo.6497559).
Translational biomedical research has a special responsibility to be transparent and of high scientific quality, as it still relies on animal testing and is the basis for clinical trials that may potentially put patients at risk. However, translational biomedical research still lags behind other fields in implementing open science practices. In addition to deep-rooted problems in the scientific incentive system, this deficit may also be due to a lack of information. Animal
researchers can already choose from a variety of tools to increase the transparency of their scientific work. We provide an overview on the tools that can be used throughout the research process, from planning to conducting and analyzing a study to publishing it. Open science practices not only raise the profile of individual scientists, but can also initiate a change in the research culture towards greater transparency and quality. There are early
indications that open science is increasingly being adopted in translational biomedical research as key players in the scientific incentive system, i.e., funders, publishers, and research institutions, support and, in some cases, already require the implementation of open science practices. However, scientists do not have to wait for the slowly evolving incentive framework to change their research habits; they can take initiative and start using open science tools for more collaboration, transparency and reproducibility today.