Publikationsdatenbank

The rise of Three Rs centres and platforms in Europe (2022)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Neuhaus, Winfried

Reininger-Gutmann, Birgit

Rinner, Beate

Plasenzotti, Roberto

Wilflingseder, Doris

De Kock, Joery

Vanhaecke, Tamara

Rogiers, Vera

Jírová, Dagmar

Kejlová, Kristina

Knudsen, Lisbeth E.

Nielsen, Rasmus Normann

Kleuser, Burkhard

Kral, Vivian

Thöne-Reineke, Christa (WE 11)

Hartung, Thomas

Pallocca, Giorgia

Leist, Marcel

Hippenstiel, Stefan

Lang, Annemarie

Retter, Ida

Krämer, Stephanie

Jedlicka, Peter

Ameli, Katharina

Fritsche, Ellen

Tigges, Julia

Buettner, Manuela

Bleich, Andre

Baumgart, Nadine

Baumgart, Jan

Meinhardt, Marcus W.

Spanagel, Rainer

Chourbaji, Sabine

Kränzlin, Bettina

Seeger, Bettina

von Köckritz-Blickwede, Maren

Sánchez-Morgado, José M.

Galligioni, Viola

Ruiz-Pérez, Daniel

Movia, Dania

Prina-Mello, Adriele

Ahluwalia, Arti

Chiono, Valeria

Gutleb, Arno C.

Schmit, Marthe

van Golen, Bea

van Weereld, Leane

Kienhuis, Anne

van Oort, Erica

van der Valk, Jan

Smith, Adrian

Roszak, Joanna

Stępnik, Maciej

Sobańska, Zuzanna

Olsson, I. Anna S.

Franco, Nuno Henrique

Sevastre, Bogdan

Kandarova, Helena

Capdevila, Sara

Johansson, Jessica

Cederroth, Christopher R.

Sandström, Jenny

Ragan, Ian

Bubalo, Nataliia

Spielmann, Horst

Quelle

Alternatives to laboratory animals : ATLA

Bandzählung: 50

Heftzählung: 2

Seiten: 90 – 120

ISSN: 0261-1929

Sprache

Englisch

Verweise

URL (Volltext): https://journals.sagepub.com/doi/10.1177/02611929221099165

DOI: 10.1177/02611929221099165

Pubmed: 35578444

Kontakt

Institut für Tierschutz, Tierverhalten und Versuchstierkunde

Königsweg 67
14163 Berlin
+49 30 838 61146
tierschutz@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years. The term 'the Three Rs', which stands for the Replacement, Reduction and Refinement of animal experiments, is inseparably linked in this context. A common goal within the Three Rs scientific community is to develop predictive non-animal models and to better integrate all available data from in vitro, in silico and omics technologies into regulatory decision-making processes regarding, for example, the toxicity of chemicals, drugs or food ingredients. In addition, it is a general concern to implement (human) non-animal methods in basic research. Toward these efforts, there has been an ever-increasing number of Three Rs centres and platforms established over recent years - not only to develop novel methods, but also to disseminate knowledge and help to implement the Three Rs principles in policies and education. The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes gave a strong impetus to the creation of Three Rs initiatives, in the form of centres and platforms. As the first of a series of papers, this article gives an overview of the European Three Rs centres and platforms, and their historical development. The subsequent articles, to be published over the course of ATLA's 50th Anniversary year, will summarise the current focus and tasks as well as the future and the plans of the Three Rs centres and platforms. The Three Rs centres and platforms are very important points of contact and play an immense role in their respective countries as 'on the ground' facilitators of Directive 2010/63/EU. They are also invaluable for the widespread dissemination of information and for promoting implementation of the Three Rs in general.