Publikationsdatenbank

Advances in diagnosis of gastrointestinal nematodes in livestock and companion animals (2022)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Rinaldi, Laura

Krücken, J. (WE 13)

Martinez-Valladares, M.

Pepe, P.

Maurelli, M. P.

de Queiroz, C.

Castilla Gómez de Agüero, V.

Wang, T.

Cringoli, Giuseppe

Charlier, J.

Gilleard, J. S.

von Samson-Himmelstjerna, G. (WE 13)

Quelle

Advances in parasitology

Bandzählung: 118

Seiten: 85 – 176

ISSN: 0065-308x

Sprache

Englisch

Verweise

URL (Volltext): https://www.sciencedirect.com/science/article/abs/pii/S0065308X22000318?via%3Dihub

DOI: 10.1016/bs.apar.2022.07.002

Pubmed: 36088084

Kontakt

Institut für Parasitologie und Tropenveterinärmedizin

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 62310
parasitologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Diagnosis of gastrointestinal nematodes in livestock and companion animals has been neglected for years and there has been an historical underinvestment in the development and improvement of diagnostic tools, undermining the undoubted utility of surveillance and control programmes. However, a new impetus by the scientific community and the quickening pace of technological innovations, are promoting a renaissance of interest in developing diagnostic capacity for nematode infections in veterinary parasitology. A cross-cutting priority for diagnostic tools is the development of pen-side tests and associated decision support tools that rapidly inform on the levels of infection and morbidity. This includes development of scalable, parasite detection using artificial intelligence for automated counting of parasitic elements and research towards establishing biomarkers using innovative molecular and proteomic methods. The aim of this review is to assess the state-of-the-art in the diagnosis of helminth infections in livestock and companion animals and presents the current advances of diagnostic methods for intestinal parasites harnessing (i) automated methods for copromicroscopy based on artificial intelligence, (ii) immunodiagnosis, and (iii) molecular- and proteome-based approaches. Regardless of the method used, multiple factors need to be considered before diagnostics test results can be interpreted in terms of control decisions. Guidelines on how to apply diagnostics and how to interpret test results in different animal species are increasingly requested and some were recently made available in veterinary parasitology for the different domestic species.