Publikationsdatenbank

World association for the advancement of veterinary parasitology (WAAVP):
third edition of guideline for evaluating the efficacy of equine anthelmintics (2022)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Nielsen, Martin K.

von Samson-Himmelstjerna, Georg (WE 13)

Kuzmina, Tetiana A.

van Doorn, Deborah C. K.

Meana, Aranzazu

Rehbein, Steffen

Elliott, Timothy

Reinemeyer, Craig R.

Quelle

Veterinary Parasitology

Bandzählung: 303

Seiten: Artikel 109676

ISSN: 0304-4017

Sprache

Englisch

Verweise

URL (Volltext): https://www.sciencedirect.com/science/article/pii/S0304401722000309

DOI: 10.1016/j.vetpar.2022.109676

Pubmed: 35164972

Kontakt

Institut für Parasitologie und Tropenveterinärmedizin

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 62310
parasitologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

This guideline have been developed to assist in the design, execution, and interpretation of studies to assess the efficacy of anthelmintic drugs against internal parasites of equines, including nematodes, cestodes, and larval instars of Gasterophilus spp. The design and execution of critical and controlled studies are outlined, and their advantages and disadvantages are discussed. Unique considerations for specific target parasites are included. Information is also provided on selection of animals, procedures for randomization, housing, feeding, dosage titration, dosage confirmation and field studies, record keeping and necropsy procedures. Finally, this document includes guidance for group size determination and statistical analysis of study results. This guideline should assist investigators in the evaluation of anthelmintic drugs in horses by using comparable and standardized procedures in studies with appropriate numbers of animals.