Publikationsdatenbank

Development of quality control ranges, breakpoints, and interpretive categories for antimicrobial agents used in veterinary medicine : VET02 : this guideline discusses the necessary and recommended data for selecting appropriate quality control ranges, breakpoints, and interpretive categories for antimicrobial agents for veterinary use:
a guideline for global application developed through the Clinical and Laboratory Standards Institute consensus process (2021)

Art

Buchautorenschaft

Autoren

Martinez, Marilyn N.

Papich, Mark G.

Hunter, Robert P.

Li, Xian-Zhi

Rose, Markus

Silley, Peter

Turnidge, John D.

Watts, Jeffrey L.

Abbeloos, Elke

Bade, Donald J.

Hayes, Joshua

Loy, John Dustin

Ludwig, Carolin

Moyaert, Carolin

Schwarz, Stefan (WE 7)

Sweeney, Michael T.

Quelle

4. Auflage

Malvern, PA: Clinical Laboratory Standards (CLSI), 2021. Documents / Clinical and Laboratory Standards Institute ; volume 41, number 2 — ix, 88 Seiten

ISBN: 978-1-68440-103-1

Schriftenreihe

Documents / Clinical and Laboratory Standards Institute, volume 41, number 2. Band

Sprache

Englisch

Verweise

URL (Volltext): https://clsi.org/media/u02pukia/vet02ed4_sample.pdf

Kontakt

Institut für Mikrobiologie und Tierseuchen

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51843 / 66949
mikrobiologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Clinical and Laboratory Standards Institute guideline VET02-Development of Quality Control Ranges, Breakpoints, and Interpretive Categories for Antimicrobial Agents Used in Veterinary Medicine provides recommendations for developing QC ranges, agar disk diffusion zones of inhibition breakpoints, and dilution minimal inhibitory concentration breakpoints for antimicrobial susceptibility tests for aerobic bacteria isolated from animals and performed by CLSI antimicrobial susceptibility testing standards. It describes the data used by the Subcommittee on Veterinary Antimicrobial
Susceptibility Testing to establish these QC ranges, breakpoints, and interpretive categories for antimicrobial agents intended for veterinary use. Host-specific pharmacokinetics, in vitro drug characteristics, distributions of microorganisms, and correlation of test results with outcome statistics are described for interpretation of test results. As antimicrobial agents are used in practice, additional experience accrued may be used to reassess QC ranges, breakpoints, or interpretive categories. Users of this guideline should understand that susceptibility test results cannot predict clinical outcomes with absolute certainty. Susceptibility test results should be used along with experienced clinical judgment and laboratory support to reach conclusions resulting in the best possible outcome for the patient.