Oertzenweg 19 b
14163 Berlin
+49 30 838 62422
kleintierklinik@vetmed.fu-berlin.de
Objectives:
Anaplasma phagocytophilum is considered to be the most important rickettsial pathogen to affect cats. Transmitted by Ixodes ricinus ticks in Central Europe the organism can cause granulocytic anaplasmosis. In the United Kingdom, cats (0-2%) and ticks found on cats (1%) were tested positive
by PCR. Aims of this study were to assess the frequency of positive test results for A. phagocytophilum in cats in Germany, Austria and Switzerland, and to evaluate clinical and laboratory manifestations in PCR-positive tested cats.
Methods:
Results of direct (PCR) and indirect detection methods (IFAT), requested by veterinarians in Germany, Austria and Switzerland in the years from 2008 to 2020 in a German laboratory, were included. The treating veterinarians of PCR-positive cats were contacted by means of telephone calls.
Results:
229/1579 cats (15%) were tested positive by direct (PCR 26/710 cats, 4%) and/or indirect detection methods (IFAT 207/914 cats, 23%). In 17/26 cats with a positive A. phagocytophilum PCR, additional information about clinical signs and laboratory abnormalities was obtained. In 12/17 cats without
known concurrent diseases the most common manifestations were lethargy (92%), fever (83%) and thrombocytopenia (58%). The remaining 5 PCR-positive cats were additionally diagnosed with Mycoplasma haemofelis infections (n=2), lymphoma, hyperthyroidism and ileus.
Statement (conclusions):
Infections with A. phagocytophilum should be considered as differential diagnoses in cats with tick infestation, lethargy, fever and thrombocytopenia. The clinical and laboratory manifestations are in accordance with published case reports in cats. Ectoparasitic prophylaxis in cats is recommended
throughout the entire year.