Publikationsdatenbank

Animal models of Alzheimer's disease should be controlled for Roseolovirus (2020)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Denner, Joachim (WE 5)

Tanzi, Rudolph

Jacobson, Steve

Quelle

Journal of Alzheimer's disease : JAD

Bandzählung: 77

Heftzählung: 2

Seiten: 543 – 545

ISSN: 1387-2877

Sprache

Englisch

Verweise

URL (Volltext): https://content.iospress.com/articles/journal-of-alzheimers-disease/jad200591

DOI: 10.3233/JAD-200591

Pubmed: 32804089

Kontakt

Institut für Virologie

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51833
virologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Animal models to study Alzheimer's disease (AD) pathogenesis are under development. Since herpesviruses have been postulated to be capable of triggering the pathogenic process, AD animal models (mouse, pig, and non-human primates) should be controlled for the presence of these viruses. Only virus-free models allow studying the genetic factors and the effect of adding viruses. Roseoloviruses such as human herpesvirus 6 and the related viruses in the animals are the main topic of this commentary.