Publication Database

Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines (2021)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autor

Denner, Joachim (WE 5)

Quelle

Translational oncology

Bandzählung: 14

Heftzählung: 1

Seiten: Artikel 100941

ISSN: 1936-5233

Sprache

Englisch

Verweise

URL (Volltext): https://www.sciencedirect.com/science/article/pii/S1936523320304332

DOI: 10.1016/j.tranon.2020.100941

Pubmed: 33221683

Kontakt

Institut für Virologie

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51833
virologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Many tumour cells express on their surface proteins of endogenous retroviruses (ERVs) and there are suggestions to use these retroviral antigens as target for anti-tumour vaccines. However, until now there is no convincing data showing that this strategy works, in contrast, there are considerations suggesting that this strategy may be harmful if applied.