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The facial expressions of animals provide valuable information on their well-being. Therefore, facial action coding systems, such as the Mouse Grimace Scale, were developed for various species in recent years. For instance, squeezed eyes, stiffened whiskers, laid-back ears, and nose or cheek bulges can indicate pain in mice. To facilitate the use of the Mouse Grimace Scale we made efforts to automatize it using deep learning and to create an app that is freely available for everyone – with the aim to minimize suffering of mice in the laboratory [1].