Publikationsdatenbank

Accuracy of a magnetic resonance imaging-based 3D printed stereotactic brain biopsy device in dogs (2020)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Gutmann, Sarah

Winkler, Dirk

Müller, Marcel

Möbius, Robert

Fischer, Jean-Pierre

Böttcher, Peter (WE 20)

Kiefer, Ingmar

Grunert, Ronny

Flegel, Thomas

Quelle

Journal of veterinary internal medicine

Bandzählung: 34

Heftzählung: 2

Seiten: 844 – 851

ISSN: 0891-6640

Sprache

Englisch

Verweise

URL (Volltext): https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.15739

DOI: 10.1111/jvim.15739

Pubmed: 32091636

Kontakt

Klein- und Heimtierklinik

Oertzenweg 19 b
14163 Berlin
+49 30 838 62422
kleintierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Background:
Brain biopsy of intracranial lesions is often necessary to determine specific therapy. The cost of the currently used stereotactic rigid frame and optical tracking systems for brain biopsy in dogs is often prohibitive or accuracy is not sufficient for all types of lesion.

Objectives:
To evaluate the application accuracy of an inexpensive magnetic resonance imaging-based personalized, 3D printed brain biopsy device.

Animals:
Twenty-two dog heads from cadavers were separated into 2 groups according to body weight (<15 kg, >20 kg).

Methods:
Experimental study. Two target points in each cadaver head were used (target point 1: caudate nucleus, target point 2: piriform lobe). Comparison between groups was performed using the independent Student's t test or the nonparametric Mann-Whitney U Test.

Results:
The total median target point deviation was 0.83 mm (range 0.09-2.76 mm). The separate median target point deviations for target points 1 and 2 in all dogs were 0.57 mm (range: 0.09-1.25 mm) and 0.85 mm (range: 0.14-2.76 mm), respectively.

Conclusion and Clinical Importance:
This magnetic resonance imaging-based 3D printed stereotactic brain biopsy device achieved an application accuracy that was better than the accuracy of most brain biopsy systems that are currently used in veterinary medicine. The device can be applied to every size and shape of skull and
allows precise positioning of brain biopsy needles in dogs.