Publikationsdatenbank

Association between disease severity, Heart Rate Variability (HRV) and serum cortisol concentrations in horses with acute abdominal pain (2020)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Gehlen, Heidrun (WE 17)

Faust, Maria-Dorothee (WE 17)

Grzeskowiak, Remigiusz M.

Trachsel, Dagmar S. (WE 17)

Quelle

Animals

Bandzählung: 10

Heftzählung: 9

Seiten: Artikel 1563

ISSN: 2076-2615

Sprache

Englisch

Verweise

URL (Volltext): https://www.mdpi.com/2076-2615/10/9/1563

DOI: 10.3390/ani10091563

Pubmed: 32887514

Kontakt

Pferdeklinik

Oertzenweg 19 b
14163 Berlin
+49 30 838 62299 / 62300
pferdeklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Heart rate variability (HRV) is a noninvasive technique to detect changes in the autonomous nervous system. It has rarely been investigated in horses with colic. Therefore, the objective was to assess the evolution of HRV parameters and cortisol concentrations in horses with colic. The 43 horses included in this study were categorized into three groups according to the treatment (1, surgical; 2, conservative; 3, euthanized). The HRV and laboratory variables were measured at admission (T1), the day after admission (T2), and at discharge (T3) and compared between groups and over time with an ANOVA with Bonferroni correction. Relationships between the HRV parameters themselves and the laboratory variables was assessed by Pearson correlation coefficients. Evolution of the heart rate (HR) over time, mean normal to normal R intervals (meanNN) and cortisol concentrations indicate a decreased sympathetic stimulation over time in group 1 and 2, in contrast to group 3. For group 3, the meanNN and HR differed significantly to group 2 at T1 and to group 1 and 2 at T2. Treatment induced a change in the HRV and cortisol response in horses managed conservatively or surgically but not in horses that required euthanasia. However, further studies are required to assess the validity of HRV analyses in horses with colic.