Publikationsdatenbank

COVID-19:
epidemiology, evolution, and cross-disciplinary perspectives (2020)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Sun, Jiumeng

He, Wan-Ting

Wang, Lifang

Lai, Alexander

Ji, Xiang

Zhai, Xiaofeng

Li, Gairu

Suchard, Marc A.

Tian, Jin

Zhou, Jiyong

Veit, Michael (WE 5)

Su, Shuo

Quelle

Trends in molecular medicine

Bandzählung: 26

Heftzählung: 5

Seiten: 483 – 495

ISSN: 1471-499x

Sprache

Englisch

Verweise

URL (Volltext): https://www.sciencedirect.com/science/article/abs/pii/S1471491420300654

DOI: 10.1016/j.molmed.2020.02.008

Pubmed: 32359479

Kontakt

Institut für Virologie

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51833
virologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

The recent outbreak of COVID-19 in Wuhan turned into a public health emergency of international concern. With no antiviral drugs nor vaccines, and the presence of carriers without obvious symptoms, traditional public health intervention measures are significantly less effective. Here, we report the epidemiological and virological characteristics of the COVID-19 outbreak. Originated in bats, 2019-nCoV/ severe acute respiratory syndrome coronavirus (SARS-CoV)-2 likely experienced adaptive evolution in intermediate hosts before transfer to humans at a concentrated source of transmission. Similarities of receptor sequence binding to 2019-nCoV between humans and animals suggest a low species barrier for transmission of the virus to farm animals. We propose, based on the One Health model, that veterinarians and animal specialists should be involved in a cross-disciplinary collaboration in the fight against this epidemic.