Publikationsdatenbank

Trilateral relationship:
ascaris, microbiota, and host cells (2021)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Midha, Ankur (WE 6)

Ebner, Friederike (WE 6)

Schlosser-Brandenburg, Josephine (WE 6)

Rausch, Sebastian (WE 6)

Hartmann, Susanne (WE 6)

Quelle

Trends in parasitology

Bandzählung: 37

Heftzählung: 3

Seiten: 251 – 262

ISSN: 1471-4922

Sprache

Englisch

Verweise

URL (Volltext): https://www.sciencedirect.com/science/article/pii/S1471492220302427

DOI: 10.1016/j.pt.2020.09.002

Pubmed: 33008723

Kontakt

Institut für Immunologie

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 51834
immunologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Ascariasis is a globally spread intestinal nematode infection of humans and a considerable concern in pig husbandry. Ascaris accomplishes a complex body migration from the intestine via the liver and lung before returning to the intestine. Tissue migration and the habitat shared with a complex microbial community pose the question of how the nematode interacts with microbes and host cells from various tissues. This review addresses the current knowledge of the trilateral relationship between Ascaris, its microbial environment, and host cells, and discusses novel approaches targeting these interactions to combat this widespread infection of livestock and man.