Publikationsdatenbank

A 3D-printed simulator of the rat for laboratory animal training courses (2019)

Art

Vortrag

Autoren

Corte, Giuliano Mario (WE 1)

Humpenöder, Melanie (WE 11)

Pfützner, Marcel (WE 1)

Merle, Roswitha (WE 16)

Ladwig-Wiegard, Mechthild (WE 11)

Thöne-Reineke, Christa (WE 11)

Plendl, Johanna (WE 1)

Kongress

The 10th meeting of Young Generation of Veterinary Anatomists

Bukarest, 24. – 26.07.2019

Quelle

Proceedings : the 10th Meeting of the Young Generation of Veterinary Anatomists – YGVA 2019 : July 24 – 26, 2019 București, România — Meeting of the Young Generation of Veterinary Anatomists ; Florin Stǎnicǎ (Hrsg.)

Bucureşti: Ex Terra Aurum, 2019 — S. 22–23

ISBN: 978-606-8974-15-6

Sprache

Englisch

Verweise

URL (Volltext): https://ygva2019.usamv.ro/ygva-files/YGVA%202019%20Proceedings.pdf

Kontakt

Institut für Veterinär-Epidemiologie und Biometrie

Königsweg 67
14163 Berlin
+49 30 838 56034
epi@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Introduction:
In the past years, simulator-based training has become increasingly popular and important in veterinary sciences. For laboratory animal training courses, several rat simulators are currently offered on the international market.
According to the suppliers, different procedures can be practiced including cannulation of blood vessels, intravenous application and administration by oral gavage or subcutaneous injection. The aim of this study is to anatomically evaluate the present simulators and accordingly to conduct a requirement
analysis. This analysis will then serve as basis for 3D printing an anatomically correct simulator that includes all necessary functional features. This study can be regarded as a feasibility study to determine whether complex anatomical structures can be printed via 3D-printing technology.

Materials and Methods:
The team consists of veterinary anatomists, of experts in animal experimentation, of a specialist in statistics and of an engineer with medical background. Two groups will evaluate the existing simulators using specific evaluation sheets, i.e., anatomists focusing on morphology and the experts in animal experimentations are focusing on functions. For the creation of the 3D computer model, an already existing µ-CT of a 12-months-old Wistar rat serves as a template. Amongst others, software CATIA V5, Slicer and AutoCAD 2000 are employed and a multi-material printer (Stratasys J750) is used.

Results and Discussion:
The first evaluations show that from the standpoint of anatomists these models are not realistic and fail to mimic the correct anatomy of the oral cavity,
larynx, pharynx, esophagus and the haptics of the tissue and blood vessels. By using multi-material printers, the haptics and lifelike morphology can be improved significantly. Using a combination of different UV-curing photopolymers and silicones showed the most satisfying results.

Conclusion:
The need for anatomically correct simulators is underestimated. Simulators must mimic the realistic anatomy regarding anatomical details, dimensions
and structures including tissue texture and haptics. The method employed can ultimately be adapted to produce any desired anatomical model or simulator, which then can be used for anatomical teaching.