Publikationsdatenbank

Comparative anatomy and pathology of uterine disorders in pet rabbits (oryctolagus cuniculus) and guinea pigs (cavia porcellus) (2019)

Art

Poster

Autoren

Bertram, Christof A. (WE 12)

Müller, Kerstin (WE 20)

Ewringmann, Anja

Klopfleisch, Robert (WE 12)

Kongress

ACVP & ASVCP 2019 Concurrent Annual Meeting

San Antonio, 09. – 13.11.2019

Quelle

Sprache

Englisch

Verweise

URL (Volltext): https://cdn.ymaws.com/www.acvp.org/resource/resmgr/meetings_&_events/2019/2019_acvp_and_asvcp_final_ab.pdf

Kontakt

Institut für Tierpathologie

Robert-von-Ostertag-Str. 15
14163 Berlin
+49 30 838 62450
pathologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Background:
Rabbits and guinea pigs are popular small mammal pets. Although uterine disorders seem to be common in both species, comparison has not been previously made.

Objective:
To describe particularities of uterine anatomy and pathology in pet rabbits and guinea pigs.

Methods:
Uterine gross and microscopic anatomy was investigated in animals without uterine disorders. Frequency and age distribution of uterine disorders were analyzed retrospectively of cases examined between 1995 and 2018.

Results:
Rabbits and guinea pigs have auterus duplex bicollis. The cervix of guinea pigs is lined by characteristic mucinous glands. Uterine disorders were found in 27.1% and 17.4% of post-mortem examinations in rabbits and guinea pigs, respectively. For both species, incidence of neoplasia and hyperplasia increased with age. Whereas epithelial tumors were very frequent and almost exclusively malignant in rabbits, they were less common and mostly benign in guinea pigs. Mesenchymal tumors occurred occasionally and were mostly benign in both species. Uterine inflammation was most frequent in young to middle-aged rabbits and guinea pigs with similar disease incidences. Uterine disorder types that were exclusively found in rabbits were hydro/mucometra, endometrial venous aneurysms and malformations.Specific disorders of guinea pigs were decidual proliferations (deciduoma, decidualization, deciduosarcoma) and endocervical proliferations (hyperplasia and neoplasia).

Conclusion:
Although age distributions of uterine neoplasia, hyperplasia and inflammation was quite similar between rabbits and guinea pigs, there were substantial differences in the frequency of the different uterine disorder. Anatomical particularities of guinea pigs are the endocervical glands that occasionally had proliferative or neoplastic disease.