Publikationsdatenbank

Evaluation of serum calcium dynamics within the first three days after parturition and the associated risk of acute puerperal metritis (2019)

Art

Poster

Autoren

Venjakob, Peter (WE 19)

Staufenbiel, Rudolf (WE 18)

Heuwieser, Wolfgang (WE 19)

Borchardt, Stefan (WE 19)

Kongress

First Symposium of the European College of Animal Reproduction

Vienna, Austria, 04. – 06.07.2019

Quelle

Proceedings : European College of Animal Reproduction First Symposium 4 - 6 July 2019 Vienna, Austria — European College of Animal Reproduction Symposium (ECAR) (Hrsg.)

Vienna: ECAR, 2019 — S. 65

Sprache

Englisch

Verweise

URL (Volltext): https://www.vetmeduni.ac.at/fileadmin/ECAR_2019_Proceedings.pdf

Kontakt

Nutztierklinik

Königsweg 65
14163 Berlin
+49 30 838 62261
klauentierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Periparturient hypocalcemia is frequently observed and considered as a gateway disease with an associated risk for other clinical diseases and poor performance. Multiparous cows especially as they progress to the third or greater lactation have more difficulties to maintain calcium homeostasis around parturition. The objectives of this study were 1) to evaluate postpartum serum calcium dynamics, considering parity, and 2) to evaluate the effect of serum
calcium concentration on day 0, 1, and 3 postpartum on the risk of acute puerperal metritis (APM). The study was conducted on a commercial dairy farm in northern Germany from 2011 to 2014. Holstein dairy cows (n = 4,043) were enrolled at the day of calving. Calving difficulties, such as dystocia, twins or stillbirth were recorded. Blood samples were obtained on d 0, 1, and 3 after calving and analysed for serum calcium concentration. Animals were examined daily for clinical symptoms of retained placenta, APM, mastitis, and displaced abomasum until 10 DIM. To determine serum calcium dynamics postpartum, repeated measures ANOVA with first-order autoregressive covariance was performed. A logistic regression model was used to evaluate the effect of serum calcium concentration on the risk of incurring metritis. Serum calcium concentration was affected by time (P = 0.003), parity (P < 0.001), and APM (P < 0.001). There was an interaction of time*parity (P < 0.001), time*APM (P < 0.001), and time*parity*APM (P = 0.091). Mean serum calcium concentration 0 – 3 DIM was 2.19 mmol/L, 2.14 mmol/L, 2.06 mmol/L, and 1.98 mmol/L for cows in first, second, third and ≥ fourth lactation, respectively. The nadir of serum calcium concentration occurred on d 1 in primiparous cows and on d 3 after calving in multiparous cows. The overall incidence of APM was 11.8 %. Incidence of APM was 20.2 % and 8.6 % in primiparous and multiparous cows, respectively. Serum calcium concentration on d 3 after calving was most predictive for APM (odds ratio = 0.194). Primiparous cows with low serum calcium concentration had the highest predicted probability to develop APM. In conclusion, the present study emphasizes that there is a profound dynamic in serum calcium concentration in the first few days of lactation.
Serum calcium concentration on the first 3 DIM differed not only between primiparous and multiparous cows, but also within the group of multiparous cows. To predict future APM serum calcium concentration on d 3 was most suitable. However, it cannot be elucidated whether hypocalcemia is a risk factor for APM or a concomitant circumstance of the disease.