Publikationsdatenbank

Extended-spectrum beta-lactamase and AmpC beta-lactamase-producing Entero-bacteriaceae in turkey fattening farms:
a cross-sectional study (2019)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Friese, A. (WE 10)

Morgenstern Lu, H. (WE 10)

Merle, R. (WE 16)

Roesler, U. (WE 10)

Quelle

Berliner und Münchener tierärztliche Wochenschrift : BMTW

Bandzählung: 132

Seiten: Artikel 18025

ISSN: 1439-0299

Sprache

Englisch

Verweise

URL (Volltext): https://vetline.de/extended-spectrum-beta-lactamase-and-ampc-beta-lactamase-producing-enterobacteriaceae-in-turkey-fattening-farms-a-cross-sectional-study/150/3130/110645

DOI: 10.2376/0005-9366-18025

Kontakt

Institut für Tier- und Umwelthygiene

Robert-von-Ostertag-Str. 7-13
14169 Berlin
+49 30 838 51845
tierhygiene@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Extended-spectrum beta-lactamase (ESBL) and AmpC beta-lactamase (AmpC)-producing Enterobacteriaceae are found in companion and farm animals worldwide. For turkeys, however, limited data exist. A cross-sectional study of 48 conventional turkey fattening farms was, therefore, conducted throughout Germany. Rearing as well as fattening flocks within the same farms were studied by investigating pooled faeces, boot swabs and dust samples. In total, 70.8% (34/48) of all farms were positive for ESBL/AmpC-producing Enterobacteriaceae and 60.4% (29/48) for ESBL/AmpCproducing Escherichia coli (E. coli). When comparing the ESBL/AmpC status of rearing and fattening flocks no significant differences were found. The use of antibiotics was documented, however, no obvious impact could be found. The highest detection rates of the resistant bacteria appeared in boot swabs (46.7% for ESBL/AmpCproducing Enterobacteriaceae, 39.1% for ESBL/AmpC-producing E. coli) followed by pooled faeces (38.8% and 30.4%, respectively) and dust samples (25% and 18.5%, respectively). Isolates were tested for common ESBL genes (blaCTX-M, blaSHV, blaTEM) and CIT-type AmpC beta-lactamase encoding genes including the common blaCMY-2. Genes encoding for CTX-M type were found most frequent (88.3%, 121/137), with CTX-M-1 most often (41.6%) followed by CTX-M-14 (20.7%), CTX-M-15 (17.3%), CTX-M-32 (7.4%), CTX-M-27 (6.6%) and CTX-M-55 (0.8%). Also other ESBL encoding genes such as SHV-2, SHV-12 and TEM-52 as well as the AmpC beta-lactamase CMY-2 encoding gene were found sporadically. ESBL/AmpC-producing E. coli occur regularly in German turkey fattening farms, however, with lower prevalences compared to other animal species.