Publikationsdatenbank

Randomised clinical trial showing the curative effect of bandaging on M2-stage lesions of digital dermatitis in dairy cows (2019)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Klawitter, Marcus (WE 18)

Döpfer, Dörte

Braden, Theo Broderick

Amene, Ermias

Müller, K. E. (WE 18)

Quelle

Vet record open

Bandzählung: 6

Seiten: Article e000264

ISSN: 2052-6113

Sprache

Englisch

Verweise

URL (Volltext): https://vetrecordopen.bmj.com/content/vetreco/6/1/e000264.full.pdf

DOI: 10.1136/vetreco-2017-000264.

Kontakt

Nutztierklinik

Königsweg 65
14163 Berlin
+49 30 838 62261
klauentierklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Objectives and design This trial evaluated the effect
of bandaging of acute painful ulcerative bovine digital
dermatitis (DD) lesion (stage M2) in dairy cows, tested
using two different topical treatments.
Design Randomised clinical trial.
Setting This study was conducted using Holstein-Friesian
cows ranging in age from heifers to fourth lactation in a
single dairy herd and diagnosed with acute ulcerative DD
lesions (stage M2) on the first examination (week 0). Cows
were randomly assigned into either a non-bandaged or
bandaged group across two treatment conditions: topical
chlortetracycline spray (CTC) and Intra Hoof-Fit Gel (IHF).
Lesions received standardised bandaging and treatment
on a weekly basis. Unhealed lesions could receive up to
five repeated treatments, at weekly intervals, within a
four-week period. Both M-stage and locomotion were also
evaluated and scored weekly. Cows with healthily formed
skin (stage M0) were deemed healed and subsequently
released from the study.
Results In total, 163 M2 lesions were diagnosed at
week 0. Bandaged M2 lesions had a significantly higher
probability of cure than non-bandaged lesions regardless
of treatment type (HR: 4.1; P<0.001; 95 per cent CI:
2.5 to 6.8). Most healing occurred within the first three
weeks of trial. Furthermore, bandaged lesions (group 2
and group 4) were significantly less likely to progress
into the chronic hyperkeratotic or proliferative stage
(M4) than non-bandaged lesions in group 1 and group 3
(HR: 0.10; P<0.001; 95 per cent CI: 0.04 to 0.22). Out of
concern for the cow’s wellbeing, this study investigated
the effects of bandaging on locomotion. Bandaging had
no effect on locomotion for either cows treated with CTC
(group 1: median Sprecher score, 2; IQR=1–2; group 2:
median Sprecher score, 2; IQR=1–3; P=0.3) or IHF (group
3: median Sprecher score, 2; IQR=1–2; group 4: median
Sprecher score, 2; IQR=1–3; P=0.3).