Publikationsdatenbank

Evaluation of clinical, laboratory, imaging findings and outcome in 99 dogs with leptospirosis (2017)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Knöpfler, S

Mayer-Scholl, A (WE 12)

Luge, E

Klopfleisch, Robert (WE 12)

Gruber, Achim Dieter (WE 12)

Nöckler, Karsten (WE 12)

Kohn, Barbara (WE 20)

Quelle

The Journal of small animal practice : JSAP

Bandzählung: 58

Heftzählung: 10

Seiten: 582 – 588

ISSN: 0022-4510

Verweise

URL (Volltext): https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.12718

DOI: 10.1111/jsap.12718

Kontakt

Institut für Tierpathologie

Robert-von-Ostertag-Str. 15
14163 Berlin
+49 30 838 62450
pathologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Objective
To report clinical, laboratory and diagnostic imaging features and prognostic factors in dogs with leptospirosis from North‐East Germany.
Materials and Methods
Medical records of dogs diagnosed with leptospirosis from 2006 to 2013 were evaluated retrospectively.
Results
The study included 99 dogs. At initial presentation, the most common clinical signs were lethargy (96%), anorexia (88%), vomiting (85%), painful abdomen (39%), diarrhoea (38%), oliguria (27%) and tachypnoea (26%). Abnormal laboratory findings included anaemia (63%), thrombocytopenia (63%), leucocytosis (57%), increase of plasma urea (84%) and creatinine concentrations (81%), increased liver enzyme activities (80%), hyperbilirubinaemia (69%), hyperphosphataemia (67%), hyponatraemia (64%), hypoalbuminaemia (55%) and hypokalaemia (29%). Radiological pulmonary changes were detected in 57% of the dogs initially or during the course of disease. Severe dyspnoea, oliguria, azotaemia, hyperbilirubinaemia and severe radiological pulmonary changes were more often found in dogs that did not survive. There was renal, hepatic and pulmonary involvement in 95, 92 and 58% of the dogs, respectively, and multi‐organ lesions in 98 dogs (98%); 32 dogs died or were euthanased.
Conclusion
Several clinical and laboratory abnormalities were associated with a negative outcome; severe lung involvement was specifically associated with high mortality.