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    Plasma D-dimer Concentration in Horses with Colic (2018)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Gehlen, Heidrun (WE 17)
    El-Zahar, Heba
    Bayoumi, Yasmin
    Shalaby, Shimaa
    Shety, Tarek
    Quelle
    Advances in Animal and Veterinary Sciences; 6(1) — S. 27–32
    ISSN: 2307-8316
    Sprache
    Englisch
    Verweise
    DOI: 10.17582/journal.aavs/2018/6.1.27.32
    Kontakt
    Klinik für Pferde, allgemeine Chirurgie und Radiologie

    Oertzenweg 19 b
    14163 Berlin
    Tel.+49 30 838 62299 Fax.+49 30 838 62529
    email:pferdeklinik@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    The aim of this study was to measure the concentration of the plasma D-dimer in healthy horses and in horses with colic and to compare it before and after therapy. Thirty-two horses were included; 22 horses showed signs of abdominal pain. Horses were grouped according to clinical and laboratory examination results into healthy horses (Group I, n=10); horses with colic associated with enteritis and/or colitis (Group II, n=16) were presented with moderate intermittent abdominal pain with increased peristalsis and increased frequency of defecation; horses with colic associated with impaction of the intestine (Group III, n=6) were presented with severe abdominal pain and decreased fecal output. There was significant increase in the concentration of plasma D-dimer in horses with impaction of the intestine and horses with enteritis and/or colitis compared to clinically healthy horses. Therapeutic trials resulted in improvement of the D-dimer concentration where the concentration of plasma D-dimer was significantly decreased in horses with enteritis and/or colitis and in horses with impaction of the intestine after therapy compared to its concentration before therapy. In conclusion, D-dimer is a sensitive marker for detection of excessive fibrinolysis in horses. Higher concentration of plasma D-dimer is observed in severe cases of colic and might reflect poor prognosis.

    Plasma D-dimer Concentration in Horses with Colic (PDF Download Available). Available from: https://www.researchgate.net/publication/322228383_Plasma_D-dimer_Concentration_in_Horses_with_Colic [accessed Mar 09 2018].