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    Evidence for Human Streptococcus pneumoniae in wild and captive chimpanzees: A potential threat to wild populations (2017)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Köndgen, Sophie
    Calvignac-Spencer, Sebastien
    Grützmacher, Kim
    Keil, Verena
    Mätz-Rensing, Kerstin
    Nowak, Kathrin
    Metzger, Sonja
    Kiyang, John
    Lübke-Becker, Antina (WE 7)
    Deschner, Tobias
    Wittig, Roman M
    Lankester, Felix
    Leendertz, Fabian H (WE 7)
    Quelle
    Scientific reports; 7(1) — S. 14581
    ISSN: 2045-2322
    Sprache
    Englisch
    Verweise
    DOI: 10.1038/s41598-017-14769-z
    Pubmed: 29109465
    Kontakt
    Institut für Mikrobiologie und Tierseuchen

    Robert-von-Ostertag-Str. 7-13
    Gebäude 35
    14163 Berlin
    +49 30 838 51840 / 51843
    mikrobiologie@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Habituation of wild great apes for tourism and research has had a significant positive effect on the conservation of these species. However, risks associated with such activities have been identified, specifically the transmission of human respiratory viruses to wild great apes, causing high morbidity and, occasionally, mortality. Here, we investigate the source of bacterial-viral co-infections in wild and captive chimpanzee communities in the course of several respiratory disease outbreaks. Molecular analyses showed that human respiratory syncytial viruses (HRSV) and human metapneumoviruses (HMPV) were involved in the etiology of the disease. In addition our analysis provide evidence for coinfection with Streptococcus (S.) pneumoniae. Characterisation of isolates from wild chimpanzees point towards a human origin of these bacteria. Transmission of these bacteria is of concern because - in contrast to HRSV and HMPV - S. pneumoniae can become part of the nasopharyngeal flora, contributing to the severity of respiratory disease progression. Furthermore these bacteria have the potential to spread to other individuals in the community and ultimately into the population. Targeted vaccination programs could be used to vaccinate habituated great apes but also human populations around great ape habitats, bringing health benefits to both humans and wild great apes.