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    Novel Influenza D virus: Epidemiology, pathology, evolution and biological characteristics (2017)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Su, Shuo
    Fu, Xinliang
    Li, Gairu
    Kerlin, Fiona
    Veit, Michael (WE 5)
    Quelle
    Virulence — S. 1580–1591
    ISSN: 2150-5608
    Sprache
    Englisch
    Verweise
    DOI: 10.1080/21505594.2017.1365216
    Pubmed: 28812422
    Kontakt
    Institut für Virologie

    Robert-von-Ostertag-Str. 7-13
    Gebäude 35
    14163 Berlin
    Tel. +49 30 838 51833 Fax. +49 30 838 451847
    email:viro@zedat.fu-berlin.de

    Abstract / Zusammenfassung

    In 2011, a new virus was isolated from pigs with influenza-like symptoms and subsequently also from cattle, which are the main reservoir of the virus. It is similar to Influenza C virus (ICV), a (predominantly) human pathogen, causing respiratory disease in children. Since the virus is unable to reassort with ICV (and based on several other criteria as discussed in the text) it is now officially named as Influenzavirus D (IDV), a new genus of the Orthomyxoviridae. We summarize the epidemiology, pathology and evolution of IDV and its biological characteristics with emphasis on the only glycoprotein HEF. Based on the limited data available we finally consider whether IDV represent a public health threat.