Publication Database

Cefotaxime-resistant E. coli in dairy and beef cattle farms-Joint analyses of two cross-sectional investigations in Germany (2017)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Hille, Katja

Ruddat, Inga

Schmid, Annette

Hering, Johanna

Hartmann, Maria

von Münchhausen, Christiane

Schneider, Bettina

Messelhäusser, Ute

Friese, Anika (WE 10)

Mansfeld, Rolf

Käsbohrer, Annemarie

Hörmansdorfer, Stefan

Roesler, Uwe (WE 10)

Kreienbrock, Lothar

Forschungsprojekt

„Verbreitung von ESBL-/AmpC-bildenden Enterobakterien entlang der gesamten Masthähnchenkette: Schwachstellenanalyse und Bestimmung von Interventionspunkten“

Quelle

Preventive Veterinary Medicine

Bandzählung: 142

Seiten: 39 – 45

ISSN: 0167-5877

Sprache

Englisch

Verweise

DOI: 10.1016/j.prevetmed.2017.05.003

Pubmed: 28606364

Kontakt

Institut für Tier- und Umwelthygiene

Robert-von-Ostertag-Str. 7-13
14169 Berlin
+49 30 838 51845
tierhygiene@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Resistance to third-generation cephalosporins and other beta-lactam antibiotics is of major concern for animal and human health. Knowledge of the prevalence of resistant bacteria in primary production is an important element to estimate transmission along the stages in the food production chain and the exposure of the human population. The primary objective of this study was to determine the prevalence of cefotaxime-resistant commensal E. coli in dairy and beef cattle production units throughout Germany. Secondarily, the association between management factors and the presence of cefotaxime resistance was investigated. In total, 60 beef cattle and 52 dairy cattle production units all over Germany were included. Cefotaxime-resistant E. coli were isolated from at least one sample in 70% (95% CI: 58-83%) of the farms keeping beef cattle and 85% (95% CI: 75-94%) of the farms keeping dairy cattle. The sample prevalence was 35% (161/455; 95% CI: 31-40%) and 48% (156/323; 95% CI: 43-54%), respectively. Most factors associated with resistance to cefotaxime indicate that less intensive production results in a lower number of positive samples. For beef cattle, antimicrobial treatment of the whole animal group was significantly associated with an increased proportion of samples containing cefotaxime resistant E. coli. In addition, our results indicate that better hygiene management could improve the resistance situation on cattle farms.