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    Detection of a Yersinia pestis gene homologue in rodent samples (2016)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Giles, Timothy A
    Greenwood, Alex D (WE 12)
    Tsangaras, Kyriakos
    Giles, Tom C
    Barrow, Paul A
    Hannant, Duncan
    Abu-Median, Abu-Bakr
    Yon, Lisa
    Quelle
    PeerJ; 4 — S. e2216
    ISSN: 2167-8359
    Sprache
    Englisch
    Verweise
    DOI: 10.7717/peerj.2216
    Pubmed: 27602258
    Kontakt
    Institut für Tierpathologie

    Robert-von-Ostertag-Str. 15
    Gebäude 12
    14163 Berlin
    +49 30 838 62450

    Abstract / Zusammenfassung

    A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker.