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The present study evaluated data of free-living birds of prey and owls with fractures and luxations that were admitted to the Small Animal Clinic, Freie Universität Berlin, from January 1999 to December 2011. In addition, fractures of these birds were classified according to the AO classification (MÜLLER 2008). Inclusion criterion was at least one fracture or luxation with two orthogonal radiographs of these injuries. 806 free-living birds of prey [26 common buzzards (Buteo buteo), 172 sparrow hawks (Accipiter nisus), 148 kestrels (Falco tinnunculus), 123 hawks (Accipiter gentilis), 37 whitetailed sea eagles (Haliaeetus albicilla)] and 117 owls [49 long-eared owls (Asio otus), 48 tawny owls (Strix aluco), 20 barn owls (Tyto alba)] were included in the study. Common buzzard (40.4%, 326/806) and the long-eared owl (41.9%, 49/117) were the most often presented species with fractures and luxations. In birds of prey and owls juveniles [birds of prey 43.8% (317/724), owls 48.1% (37/77)] and female birds [birds of prey 52.9% (344/650), owls 56.8% (42/81)] dominated. In sparrow hawks significantly more female birds were presented with fractures and luxations than males (77.3%, 133/172, p≤0.023). Fractures and luxations were mostly fresh injuries [birds of prey 81.8%, (1099/1338), owls 84.5% (169/200)] and mostly closed fractures occurred [birds of prey 72.8% (974/1338), owls 71.0% (142/200)]. The main localization for fractures and luxations was the wing [birds of prey 59.8% (800/1338), owls 56.0% (112/200)]. Significant differences did exist in birds of prey and owls concerning number of injuries at shoulder-girdle and pedestals. Wings fractures and luxations occurred mostly on the humerus [birds of prey 35.6% (226/635), owls 41.8% (38/91)]. In addition, birds of prey showed significant differences in regard to the frequency of fracture localization. For instance, white-tailed sea eagles suffered significantly more fractures of carpometacarpus then other birds of prey (p≤0.034). Fractures and luxations of the shoulder-girdle were mainly located at the coracoid bone [birds of prey 52.5% (135/257), owls 48.5% (16/33)]. Fractures and luxations at the leg occurred mostly at the tibiotarsus and the fibula [birds of prey 31.3% (41/130), owls 35.5% (11/31). Fractures and luxations of the trunk and cranium were rare. In birds of prey the main localization of vertebral column injuries was the thoracic region (67.6%, 25/37) whereas owls reveald no predominant area for spinal fractures and luxations. The AO classification (MÜLLER 2008), together with own supplements, could be applied at all bones of the bird’s skeleton, except pelvic-girdle, the vertebral column and the cranium. Fracture lines at these bones were overlapping on radiographs, therefor they were not classifiable. The code 12A2 was the most frequent fracture at the humerus in birds of prey (26.5%, 49/185) and the code 12A1 in owls (21.1%, 7/33). The code 22C1 at the radius and the ulna [birds of prey 28.8% (60/208), owls 34.8% (8/23)] and the code 172A2 at the coracoid bone [birds of prey 25.6% (23/90), owls 20.0% (2/10)] dominated in birds of prey and owls. At the femur 32A2 fractures were most often identified [birds of prey 21.9% (7/32), owls 50.0% (3/6)]. 243 fractures and 25 luxations were treated conservatively (for example fractures of the single ulna, the single radius, coracoid bone, luxations of the coracoid bone) and 162 fractures and five luxations were medicated surgically (for example fractures of the femur, the humerus, of the ulna and radius, luxations of the coracoid bone). Altogether, 30.1% of birds of prey (243/806) and 23.1% of owls (27/117) were delivered to rehabilitations centers for preparing to release.