Fachbereich Veterinärmedizin


Service-Navigation

    Publikationsdatenbank

    Hypernatremia in a Cat with Toxoplasma-Induced Panencephalitis (2016)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Weingart, Christiane (WE 20)
    Gruber, Achim D (WE 12)
    Brunnberg, Mathias (WE 20)
    Kohn, Barbara (WE 20)
    Quelle
    Journal of the American Animal Hospital Association; 52(1) — S. 63–67
    ISSN: 0587-2871
    Sprache
    Englisch
    Verweise
    DOI: 10.5326/JAAHA-MS-6257
    Pubmed: 26606207
    Kontakt
    Institut für Tierpathologie

    Robert-von-Ostertag-Str. 15
    Gebäude 12
    14163 Berlin
    +49 30 838 62450

    Abstract / Zusammenfassung

    A 12 yr old female neutered Carthusian crossbreed cat was presented due to progressive neurological signs. Clinical signs included dehydration, stupor, and anisocoria. Laboratory examination revealed severe hypernatremia, azotemia, hyperglobulinemia, and an erythrocytosis. Clinical signs and hypernatremia suggested an intracranial process. Imaging studies revealed a loss of structure in the cerebrum, hypothalamus, and pituitary gland. Due to a poor prognosis, the cat was euthanatized. Histopathological examination revealed a subacute granulomatous and necrotizing panencephalitis with Toxoplasma-typical protozoa. The Toxoplasma-induced dysfunction of the hypothalamus and pituitary gland led to diabetes insipidus, which was, in combination with insufficient water intake, the most likely cause for the hypernatremia.