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    Generalised AA-Amyloidosis in a Bat (Pipistrellus pipistrellus) (1996)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Gruber, A D (WE 12)
    Linke, R P
    Quelle
    Veterinary Pathology; 33(4) — S. 428–430
    ISSN: 0300-9858
    Sprache
    Englisch
    Verweise
    Pubmed: 8817841
    Kontakt
    Institut für Tierpathologie

    Robert-von-Ostertag-Str. 15
    Gebäude 12
    14163 Berlin
    Tel.+49 30 838 62450 Fax.+49 30 838 62522

    Abstract / Zusammenfassung

    Generalized amyloidosis was found to be the cause of death in a female adult insectivorous pipistrelle bat (Pipistrellus pipistrellus) after chronic wound inflammation. Large amounts of amyloid were detected in liver, spleen, kidneys, stomach, intestine, lymphatic tissues, and endocrine and salivary glands. Congo red staining and green birefringence identified amyloid; the Congo red staining was sensitive to potassium permanganate oxidation. The amyloid was further classified immunohistochemically. The deposits reacted with two anti-human-AA-amyloid monoclonal antibodies in a peroxidase-antiperoxidase reaction, whereas no reaction was found with antibodies specific for other types of amyloid. Thus, the bat amyloid deposits were identified as generalized reactive AA-amyloidosis.