Publication Database

Genetic regulation of arrested development in nematodes:
are age-1 and daf-gene orthologs present in Dictyocaulus viviparus? (2007)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Strube, Christina

von Samson-Himmelstjerna, Georg (WE 13)

Schnieder, Thomas

Quelle

Parasitology research

Bandzählung: 101

Heftzählung: 4

Seiten: 1111 – 1115

ISSN: 0932-0113

Sprache

Englisch

Verweise

Pubmed: 17558520

Kontakt

Institut für Parasitologie und Tropenveterinärmedizin

Robert-von-Ostertag-Str. 7-13
14163 Berlin
+49 30 838 62310
parasitologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

In opposite to the free-living soil nematode Caenorhabditis elegans, the genetic regulation of hypobiosis or inhibited or arrested development in parasitic nematodes is completely unknown. In C. elegans, the daf-genes or the age-1 gene are of major importance in signaling pathways regulating arrested development. To investigate if orthologs of these genes are present in the bovine lungworm Dictyocaulus viviparus, a PCR analysis with gene-specific primer combinations was performed. No orthologs of the age-1 or daf-genes could be identified in D. viviparus. The possible differences in the role of the daf-genes concerning arrested development in parasitic and free-living nematodes will be discussed.