Publikationsdatenbank

Clinical course of a malignant peripheral nerve sheath tumor in a Siberian tiger (Panthera tigris altaica) (2010)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Steinmetz, Hanspeter W

Rütten, Maja

Ruess-Melzer, Katja

Ohlerth, Stefanie

Lischer, Christoph (WE 17)

Oevermann, Anna

Bode-Lesniewska, Beata

Hatt, Jean-Michel

Quelle

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians; 22(6) — S. 970–975

ISSN: 1040-6387

Sprache

Englisch

Verweise

Pubmed: 21088186

Kontakt

Klinik für Pferde, allgemeine Chirurgie und Radiologie

Oertzenweg 19 b
14163 Berlin
+49 30 838 62299
pferdeklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

A 14-year-old male Siberian tiger (Panthera tigris altaica) was admitted with an ulcerating mass on the right thoracic wall. Radiographic and computed tomographic evaluation indicated 2 isolated cutaneous masses without any signs of metastasis. Histology of a Tru-Cut biopsy revealed an anaplastic sarcoma with giant cells. Both tumors were resected with appropriate normal tissue margins. The size of the defect did not allow primary closure of the wound; therefore, a mesh expansion technique was attempted. Three months later, the tiger had to be euthanized due to extensive metastasis to the lungs. Histomorphological features and immunohistochemical results confirmed the diagnosis of malignant peripheral nerve sheath tumor. In contrast to domestic animal experience, the tumor had spread extensively to the lungs without local reccurrence in a short period of time. Correct diagnosis requires various immunohistochemical evaluations of the tumor tissue.