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    Stoffwechsel von 14C-markiertem Harnstoff bei konventionellen und bakterienfreien Meerschweinchen (1990)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Juhr, N C
    Franke, J
    Quelle
    Zeitschrift für Versuchstierkunde; 33(3) — S. 123–127
    ISSN: 0044-3697
    Verweise
    Pubmed: 2144936
    Kontakt
    Institut für Tierschutz und Tierverhalten

    Königsweg 67
    Gebäude 21, 1. OG
    14163 Berlin
    +49 30 838 62901
    tierschutz@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    This report deals with the utilization of 14C-labeled urea in antibiotically decontaminated, bacteria-free guinea pigs using intragastric resp. intraperitoneal administration route. With conventional animals 52% of the intragastrically administered 14C dose can be demonstrated in the exhaled air, 1.2% in organs and 41% in the urine. 1.8% were found in intestinal and faecal contents. In bacteria-free animals 29% of the activity appeared in the exhaled air, 52% in urine and 2% remain in the intestinal tract, feces and animal body. Intraperitoneal administration of 14C urea revealed 17% resp. 14% in the exhaled air, 72% resp. 66% in urine and 2% resp. 3% in intestinal tract, feces and animal body in conventional resp. bacteria-free guinea pigs.