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    Histological evaluation of the sheep's cervical spine segment 3/4--a histomorphological and histomorphometrical study (2008)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Koch, C
    Kandziora, F
    Huenigen, H (WE 1)
    Plendl, J (WE 1)
    Quelle
    Anatomia, histologia, embryologia; 37(3) — S. 200–4
    ISSN: 0340-2096
    Sprache
    Englisch
    Verweise
    Pubmed: 18162094
    Kontakt
    Institut für Veterinär-Anatomie

    Koserstr. 20
    14195 Berlin
    +49 30 838 53555
    anatomie@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    The 2-year-old sheep is a frequently used model in spinal orthopaedic research; however, so far no investigations have been performed on physiological tissue of untreated animals. In this study, the cervical spine segment 3/4 of eight 2-year-old female Merino sheep was evaluated histologically and histomorphometrically. Specimens were stained with Masson-Goldner-Trichrome, Safranin-Orange/Lightgreen, Safranin-Orange/von Kossa and Astrablue. Analysis of bone mass, mass of cartilage and mineralized cartilage in a defined region of interest was performed. A new finding of the study was that--although 2-year-old sheep is regarded as adult--tissue of the growth plate was still detected. Moreover, this study revealed that in the nucleus pulposus of the 2-year-old sheep notochordal cells are still existent, suggesting a complex remodelling of the nucleus pulposus in sheep.