Fachbereich Veterinärmedizin



    The levels of zearalenone and its metabolites in plasma, urine and faeces of horses fed with naturally, Fusarium toxin-contaminated oats (2013)

    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Songsermsakul, P
    Böhm, J
    Aurich, C
    Zentek, J (WE 4)
    Razzazi-Fazeli, E
    Journal of animal physiology and animal nutrition; 97(1) — S. 155–161
    ISSN: 0931-2439
    DOI: 10.1111/j.1439-0396.2011.01253.x
    Pubmed: 22129272
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    Abstract / Zusammenfassung

    Concentration profile of zearalenone (ZON) and its metabolites in plasma, urine and faeces samples of horses fed with Fusarium toxin-contaminated oats is described. In plasma, β-zearalenol (β-ZOL) was detected at high levels on day 10 of the study (3.21-6.24 μg/l). β-Zearalenol and α-zearalenol were the major metabolites in urine. Zearalenone, α-ZOL and β-ZOL were predominantly found in faeces. Zearalanone could also be detected in urine (1.34-5.79 μg/l) and faeces (1 μg/kg). The degree of glucuronidation was established in all sample types, approximately 100% in urine and plasma. Low per cent of glucuronidation (4-15%) was found in faeces samples. The results indicate the main conversion of ZON into β-ZOL in horse. This finding could explain why horse is not susceptible to ZON in comparison with swine which produce α-ZOL as a predominant metabolite.